From 3-5 weeks to hours.
The AI that turns the cosmetic safety dossier into an automated, traceable, and scalable flow.
OrAIsi automates the regulatory, toxicological, and documentation work around the PIF and CPSR, assisting the safety assessor.
It doesn't replace the expert.
It amplifies their operational capacity.
OrAIsi automates the manual PIF process from end to end. Where today a safety assessor spends days gathering evidence, computing exposure, tracking down NOAEL values, and writing the dossier, OrAIsi does the assembly and the assessor stays in control of every decision. The platform is grounded in authoritative regulatory sources: CosIng, ECHA / IUCLID, SCCS opinions, and Reg. 1223/2009.
We're built for safety assessors, regulatory affairs managers, and cosmetic manufacturers who need PIFs that hold up under audit. We're not built for everyone, and we don't pretend to be.
What sets OrAIsi apart
Where document managers stop, OrAIsi starts.
Cosmetic regulatory platforms (Coptis, Ecomundo, Cosmedesk) handle product lifecycle, document assembly, and compliance checks. Some include risk assessment as a feature; none lead with end-to-end automated safety reasoning.
OrAIsi is the only platform that automates the full safety reasoning chain — from INCI reconciliation through validated PIF generation — with the safety assessor in control of every decision that matters. Where document managers stop, OrAIsi starts.
90%
less time on the dossier
x50
operational capacity, without scaling resources
160→3h
expert time concentrated on judgment
380%
minimum estimated ROI
Capabilities
Capabilities.
Read the formula in any source format. Reconcile against canonical INCI.
Upload formulas, supplier lists, and Safety Data Sheets in any source format. OrAIsi parses and reconciles raw materials against the canonical INCI store, validating against CosIng annexes as ingredients enter the system. The platform handles synonym matching deterministically; the long tail falls through to an AI-assisted check the assessor reviews before it commits.
A three-tier waterfall that always lands on a defensible value.
Experimental data from IUCLID/ECHA ranked by Klimisch reliability and GLP compliance, in-silico predictions from QSAR-VEGA when experimental data isn't available, and structured manual references to CIR / EFSA / SCCS / EMA dossiers when neither resolves. SED, NOAEL, and Margin of Safety calculated per ingredient and per route.
Every claim anchored to its regulatory source.
Every claim in the PIF is anchored to its regulatory source: EU Regulation 1223/2009, the SCCS Notes of Guidance, CosIng annexes. Article 19 label compliance generated automatically. Reasoning is traceable end-to-end: when a regulator asks why a value or a verdict was chosen, the answer is one click away.
The full PIF assembled in one workflow. The platform learns under consent.
The full PIF assembled in one workflow, with Part A and Part B structured for audit. Evaluator decisions and justifications are captured as structured data; with explicit opt-in consent, that data feeds the platform's regulatory intelligence layer so accuracy improves over time and across regulatory geographies.
Why OrAIsi
Why OrAIsi.
From weeks to hours.
PIF preparation that used to take weeks of manual evidence-gathering, calculation, and writing now happens in hours. The compression is not magic — it's structured automation of the parts that don't require an assessor's judgment, with the assessor in control of the parts that do.
Defensible reasoning.
Every toxicological claim in the output is anchored to its regulatory source — EFSA, CIR, SCCS, IUCLID, the relevant CosIng annex. When a regulator or an auditor asks why, the answer is in the document. The PIF holds up because the reasoning is traceable, not because we said so.
Your formula stays yours.
Concentrations, phase composition, supplier references, and process notes are encrypted in your browser before they reach our servers. We see ingredient identifiers; we never see your IP. This isn't a policy promise. It's the architecture.
AI executes. The expert validates.
Security by architecture
Your formula concentrations never leave your browser.
Per-user encryption·EU hosting (IONOS)·GDPR·Audit under NDA
We can't structurally leak what we can't see.
Start with a 30-minute conversation.
Tell us what you're producing, who you produce for, and the regulatory frameworks you operate under. We'll show you what OrAIsi does for your specific case.